April 5, 2022
COVAIL Trial
Phase 2 Additional COVID-19 Vaccine Booster Trial
The University of Washington is seeking volunteers for the COVID-19 VAriant Immunologic Landscape (COVAIL) Trial, a phase 2 additional COVID-19 vaccine booster trial. The purpose of this clinical trial is to test the safety and effectiveness of additional COVID-19 booster doses in people who have already received a primary COVID-19 vaccination series and booster dose.
The study will enroll participants to receive either one or two additional COVID-19 booster doses. Participants will have completed a primary COVID-19 vaccination series (2 doses of Pfizer, 2 doses of Moderna, or 1 dose of Johnson & Johnson) and received a booster at least 16 weeks prior to joining the study.
Your participation in the trial will last about 12-14 months and will involve at least 7-11 in-person visits depending on the number of additional booster doses received.
Participants will undergo a screening assessment to see whether they are eligible. Study visits will involve physical exams, blood draws, nasal swab collection and vaccine injections. Participants will be asked to keep a diary of their vaccine reactions for 7-days after each injection.
To be eligible for the trial you must:
- Be 18 years of age or older
- Have received a complete primary and booster COVID-19 vaccine series no less than 16 weeks ago
- Be willing to receive additional COVID-19 booster doses
Conditions which would prevent you from participating:
- Previous SARS-CoV-2 infection less than 16 weeks ago
- Current pregnancy or breastfeeding
- Serious reactions to vaccines
Compensation:
Participants will be compensated $1025-$1450 for completing the entire study.
Clinic Location:
Our clinic is located on the 11th floor of the Ninth and Jefferson Building at Harborview Medical Center and open Monday through Friday.
If you are interested in participating, please complete our participant registry form.
For further information about this clinical trial, please contact the UW Virology Research Clinic at 206-520-4212 or vteu@uw.edu.
